Analisis Subtipe HIV-1 dan Faktor Penyebarannya pada Penderita HIV di RS. Yowari Kabupaten Jayapura, Papua

https://doi.org/10.31957/jbp.449

Authors

  • Mirna Widiyanti Balai Litbang Biomedis Papua. Jl. Kesehatan No. 10 Dok II, Jayapura, Papua. Kode Pos: 99112. Kotak Pos: 1427
  • Semuel Sandi Balai Litbang Biomedis Papua. Jl. Kesehatan No. 10 Dok II, Jayapura, Papua. Kode Pos: 99112. Kotak Pos: 1427
  • Holy A. Wibowo Pusat Biomedis dan Teknologi Dasar Kesehatan, Kementerian Kesehatan RI, Jakarta

Abstract

Acquaired immunodeficiency Syndrome (AIDS) is a symptoms caused by infection with Human Immuno-deficiency Virus (HIV). There are two types of HIV genetically distinguished as HIV-1 and HIV-2 subtype. Subtypes of HIV-1 globally have different distribution in state, where geographical factors could affected to the subtype differences. Papua is one of the provinces that have high case of HIV/AIDS. High number of people with HIV/AIDS in Papua caused by new regional area expansion and mobilization of the population in province and district area. This study was aimed to identify the sub type HIV-1 and the risk factors that correlated in the transmission of HIV-1 type. The research study was performed by cross-sectional design. There were 36 HIV patient sample respondent willing to participate in research and they were sign inform consent. Subtype HIV-1 identification was performed by used Nested-PCR, sequencing, and BLAST to found subtype HIV-1. The interview method used a questionnaires to found of  the risk factors  related to subtype HIV-1. The results of research showed that HIV-1 subtype found in people with HIV in Yowari hospital is CRF01_AE subtype (31 respondent) and subtype B ( 5 respondent). Chi-squre and Fisher exact test analysis of risk factors that influence the spread of HIV-1 subtype showed a non significant results. The research study concluded sub-type HIV-1 in patients is CRF01_AE and subtype B and  there were not correlated risk factors with HIV-1 subtype.

Key words: HIV/AIDS , type HIV-1 , CRF01_AE , Sub type-B, RS Yowari.

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Author Biographies

Mirna Widiyanti, Balai Litbang Biomedis Papua. Jl. Kesehatan No. 10 Dok II, Jayapura, Papua. Kode Pos: 99112. Kotak Pos: 1427

Balai Litbang Biomedis Papua. Jl. Kesehatan No. 10. Dok II, Jayapura, Papua. Kode Pos: 99112. Kotak Pos: 1427

Semuel Sandi, Balai Litbang Biomedis Papua. Jl. Kesehatan No. 10 Dok II, Jayapura, Papua. Kode Pos: 99112. Kotak Pos: 1427

Balai Litbang Biomedis Papua. Jl. Kesehatan No. 10. Dok II, Jayapura, Papua. Kode Pos: 99112. Kotak Pos: 1427

Holy A. Wibowo, Pusat Biomedis dan Teknologi Dasar Kesehatan, Kementerian Kesehatan RI, Jakarta

Pusat Biomedis dan Teknologi Dasar Kesehatan, Kementerian Kesehatan RI, Jakarta 

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Published

2018-07-31

Issue

Vol. 6 No. 1 (2014)

Section

Research Articles

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