Skrining Senyawa Kimia dan Uji Aktivitas Sitotoksik Ekstrak Etanol Teripang Kridou Bintik (Bohadschia argus Jeager) Asal Pantai Harlem Kabupaten Jayapura, Papua

Apianus Kilungga; Linus Y. Chrystomo; Puguh Sujarta

doi:10.31957/jbp.633

Authors

Apianus Kilungga Balai Besar Konservasi Sumber Daya Alam Papua Program Magister Biologi (PMB) Universitas Cenderawasih, Jayapura
Linus Y. Chrystomo Jurusan Biologi FMIPA, Universitas Cenderawasih Program Magister Biologi (PMB) Universitas Cenderawasih, Jayapura
Puguh Sujarta Jurusan Biologi FMIPA, Universitas Cenderawasih, Jayapura Program Magister Biologi (PMB) Universitas Cenderawasih, Jayapura

DOI:

https://doi.org/10.31957/jbp.633

Abstract

The Bohadschia argusÂ Jeager contains bioactive compounds that have the potential as antibiotics, antibacterial, antitumor, anticoagulants and anesthetics and alleviate cancer. This study aims to determine the content of chemical compoundsÂ groupÂ and to testÂ the cytotoxic activity of ethanol extract of Bohadschia argusÂ Jeager. The method for determining the groupÂ of chemical compounds was used the color reaction and precipitationÂ using chemical reagents. The method for testing cytotoxic activity using the Brine Shimp Lethality Test (BSLT), thisÂ method commonly was used to test the safety of the use of natural ingredients as traditional medicine. The results of screening of the chemical compoundÂ group ofÂ Â Bohadschia argusÂ JeagerÂ extract showed that the extract contained a lot of alkaloidsÂ secondary metabolites and few saponins. The results ofÂ testing of cytotoxic activity showed LC₅₀Â value of 878.22 ppm. Base onÂ the results of this study it can be concluded that the ethanol extract of Bohadschia argusÂ JeagerÂ has significant cytotoxic activity against Artemia salinaÂ Leach, so it can be considered as a chemotherapeutic agent.Â Â Â

Key words:Â Screening, chemical compounds,Â ethanolÂ extract, B. argus,Â BSLT.Â

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Author Biographies

Linus Y. Chrystomo, Jurusan Biologi FMIPA, Universitas Cenderawasih Program Magister Biologi (PMB) Universitas Cenderawasih, Jayapura

Biology

Puguh Sujarta, Jurusan Biologi FMIPA, Universitas Cenderawasih, Jayapura Program Magister Biologi (PMB) Universitas Cenderawasih, Jayapura

Biologi Perairan

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